The 55-year-old caused outrage on Tuesday morning when he accused the mum-of-one of lying in her explosive interview with Oprah Winfrey, as she said she had experienced suicidal thoughts.
He said: “I’m sorry, I don’t believe a word she said.
“Who did you go to? What did they say to you? I wouldn’t believe it if she read me a weather report.”
ITV has now confirmed he will not be returning to the show following the intense backlash.
Its official statement reads: “Following discussions with ITV, Piers Morgan has decided now is the time to leave Good Morning Britain.
“ITV has accepted this decision and has nothing further to add.”
Morgan attempted to clear up his comments on this morning’s episode of GMB, but it looks like it was too little too late for the presenter.
He said: “When we talked about this yesterday, I said as an all-encompassing thing I don’t believe what Meghan Markle is saying generally in this interview, and I still have serious concerns about the veracity of a lot of what she said.
“But let me just state on the record my position about mental illness and on suicide. These are clearly extremely serious things that should be taken extremely seriously, and if someone is feeling that way they should get the treatment and help they need every time.”
He has yet to release a personal statement or make any comments about his shock departure on Twitter.